More frequent checking of INR and prothrombin time in patients having such oral anticoagulants is recommneded, Specifically for the initiation and termination of androgen therapy.[ten] It can be unclear if testosterone can augment the anticoagulant response to heparin therapy or if testosterone alters the effect of other non-coumarin oral anticoagulants in a similar fashion.
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Testosterone has induced osteolysis and will be made use of with caution in individuals with hypercalcemia, which can be exacerbated in patients with metastatic breast cancer.
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Since testosterone is not utilised throughout pregnancy, there must be no certain purpose to administer the merchandise to Ladies throughout labor or obstetric delivery; safety and efficacy in these configurations have not been recognized.[3]
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